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hypopigmented macules differential diagnosis

When faced with a patient with hypopigmented macules, the differential diagnosis should include tinea versicolor, pityriasis alba, vitiligo, tuberculoid leprosy, and idiopathic guttate hypomelanosis. For example, macules can be moles (which are hyperpigmented, or darker, relative to the skin) or vitiligo lesions (which are hypopigmented or depigmented, or lighter, relative to the skin). Some people with hypopigmentation are at a higher risk for skin cancer. The hypopigmented macules progress to full depigmentation. It is necessary to perform a clinical differential diagnosis of hypopigmented lesions, including vitiligo, idiopathic guttate hypomelanosis, tinea versicolor, and postinflammatory hypopigmentation. The differential diagnosis of pityriasis alba includes the following: Postinflammatory pigment alteration. A well-defined, hypopigmented, irregularly shaped, confluent macules forming a patch that is usually found on the trunk; It presents at birth or early in childhood and persists in to adulthood remaining unchanged; Stroking, rubbing, or warming induces erythema of the adjacent normal skin Erythema, scale, and papules within these macules and patches are variable. The macules are well circumscribed and each has a central raised lesion. Nevus depigmentosus. The pigment cells or melanocytes are located at the base of the epidermis and produce the protein melanin.Melanin is carried by keratinocytes to the skin surface. Quadrichrome vitiligo features a fourth, dark-brown pigment, which surrounds hair follicles. a. ... hypopigmented macules in this 6-year-old child with pityriasis alba. Lesions of pityriasis alba are usually bilateral and located on the face, arms, and neck. Differential diagnosis Conditions to include in the differential diagnosis include the following. Differential diagnosis. Lesions often occur on the head, neck, upper extremities, trunk, and buttocks. BS consists of asymptomatic, small, irregular, hypopigmented macules characterized by a normal histological appearance, which are usually found in individuals aged 20-40 and more frequently in women than men. Introduction. Hypopigmented MF presents with hypopigmented macules and patches. Pigmenting pityriasis alba. 1 Frequency of the condition is much lower in … DISCUSSION. In these cases, the skin is more vulnerable to damage from ultraviolet rays. This is especially true of albinism. This is a broad category of differential diagnoses with variable symptomatology depending on the specific diagnosis. 1,2 The skin surrounding the lesions may be normal or mildly erythrocyanotic. Case presentation A 7-year-old girl presents with a small number of hypopigmented macules on her back that have been present for about three months (Figure 1). 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